How to Order

Submit Your Project Inquiry

Tell us about your research goals and the type of binder discovery support you need. You can submit an online project request or email us directly.

Helpful information to include

• Target name, antigen format, or target class;
• Preferred discovery format, such as scFv, VHH, or affinity maturation;
• Available antigen material, tags, labels, or biotinylation status;
• Desired selection strategy, if known, such as standard enrichment, off-rate selection, or competitive selection;
• Preferred deliverables, such as enriched pools, clone sequences, ranked binder panels, or screening-level affinity estimates;
• Desired timeline and any special project constraints.

We typically respond within 1 business day.

Technical Consultation

We schedule a short scientific consultation to understand your target, project goals, and preferred output. This helps us recommend the most appropriate yeast display workflow and selection strategy.

During the consultation, we may discuss

• Antigen format, purity, concentration, and labeling strategy;
• Library format selection, including scFv or VHH options;
• Negative selection or reagent-depletion strategies;
• Selection stringency, including equilibrium, off-rate, or competitive selection;
• Clone screening, sequencing, ranking, and optional downstream characterization.

For new targets, small antigens, difficult proteins, or affinity maturation projects, a technical consultation is strongly recommended.

Receive a Formal Quote

After technical review, we provide a written quote outlining the proposed scope, project structure, expected deliverables, estimated timeline, and pricing.

Your quote may include

• Recommended library format and screening workflow;
• Number of enrichment rounds or maturation rounds;
• FACS-based screening and selection strategy;
• Sequencing or clone-picking options;
• Final deliverables and reporting format;
• Optional add-ons, such as additional clone screening, deeper sequencing, IgG reformatting, or secondary assays.

Quotes are typically valid for 30 days unless otherwise stated.

Sign SOW and NDA, If Needed

For confidential targets, proprietary sequences, or custom experimental designs, we can provide a mutual NDA before detailed project information is exchanged.

Project documents may include

• Mutual Non-Disclosure Agreement;
• Statement of Work with clear project scope and milestones;
• Sample submission requirements;
• Payment terms and project start conditions.

Once the SOW is approved and required materials are scheduled, your project is placed into the active queue.

Submit Project Materials

Depending on the project, you may need to provide antigen, reference binders, competitor proteins, or other research-use-only materials.

Common materials include

• Purified antigen protein;
• Biotinylated or tagged antigen, if available;
• Reference antibody, ligand, or competitor molecule for competitive selection;
• Target information, sequence information, or construct details;
• Special handling requirements, storage conditions, or biosafety information.

We provide sample submission instructions that include recommended formats, shipping conditions, labeling rules, and biosafety requirements.

Most U.S. clients ship project materials by overnight courier with cold packs or dry ice when required.

Project Execution

Once materials are received and the project is initiated, DuneX performs the agreed workflow according to the approved scope of work.

Project activities may include

• Antigen labeling or staining optimization;
• Yeast display library screening;
• FACS-based enrichment and selection;
• Negative selection against tags, beads, streptavidin, or other reagents when appropriate;
• Off-rate or competitive selection for improved binder prioritization;
• Clone recovery, sequencing, and ranking;
• Screening-level binding analysis and technical reporting.

We provide project updates at key checkpoints and communicate promptly if optimization or troubleshooting is needed.

Delivery of Final Results

Final deliverables depend on the project scope and service type. Results are delivered electronically unless physical materials are specifically requested and agreed upon.

Deliverables may include

• Round-by-round enrichment summary;
• FACS gating strategy and representative plots;
• Sorted population information and selection conditions;
• Clone sequences or enriched sequence families;
• Ranked binder panel or prioritized candidate list;
• Screening-level binding or affinity estimates, where applicable;
• Technical summary with interpretation and recommended next steps.

Data can be transferred by secure electronic delivery or another agreed method.

Ongoing Support

After project completion, DuneX remains available to support follow-up questions, interpretation, and next-phase experimental planning.

Follow-up support may include

• Review of selection behavior and enrichment trends;
• Binder prioritization discussions;
• Planning for affinity maturation or additional selection rounds;
• Discussion of IgG reformatting, soluble expression, or downstream characterization;
• Design of next-phase discovery or validation experiments.

Our goal is to support your discovery workflow beyond a single project, from initial binder generation through candidate prioritization.